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Depending on the season a team may work with a specific trainer or all trainers may work with all contestants.
The trainers are responsible (in conjunction with medical personnel retained by the show) for designing comprehensive workout and nutrition plans and teaching them to the contestants.
Each season of The Biggest Loser starts with a weigh-in to determine the contestants' starting weights, which serve as the baseline for determining the overall winner.
The contestants are grouped into teams of two, each wearing separate colored t-shirts.
However, the contestants are individually responsible for implementing the principles taught.
Involved the largest cast ever with 50 contestants initially beginning the show, each representing one US state.
Contestants, regardless of their weight, are required to certify that they believe they are "in excellent physical, emotional, psychological and mental health".
The Biggest Loser: Second Chances included a one-mile foot race in its first week, an event that led to the hospitalization of two of its contestants; Rob Huizenga, the show's medical consultant, when asked about the foot race said that "If we had it to do over, we wouldn't [have done] it" and noted that in response, the show's producers have "changed a lot of the way [they] do things" (including the close monitoring of contestants' body temperatures during exercise).
The team that has lost the least percentage during that week (known as "falling below the yellow line", which refers to a line featured on a video screen showing the cutoff between safety and being at-risk) will have one member voted off (unless the team consists of only one remaining member, in which case there is no vote).
The vote is usually made by the other teams, though some episodes feature one team making the decision alone.